Cognitive ability in Down syndrome and its relationship to urinary neopterin, a marker of activated cellular immunity

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• 作者：Panagiotis Zis^a ; ^b ; ^{takiszis@gmail.com} ; André ; Strydom^a ; ^c ; David Buckley^d ; Daniel Adekitan^d ; Patrick C. McHugh^d
• 关键词：Down syndrome ; Aging ; Alzheimer&rsquo ; s disease ; Memory ; Neopterin ; Oxidative stress
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：636
• 期：Complete
• 页码：254-257
• 全文大小：454 K
• 卷排序：636

文摘

Urine neopterin has potential as a biomarker for memory decline in Down syndrome. Urine neopterin can help to track progression of MCI to Alzheimer’s disease. The evidence for the role of immune response and oxidative stress in DS is growing.