Facilitation of tactile working memory by top-down suppression from prefrontal to primary somatosensory cortex during sensory interference

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• 作者：Petri Savolainen^a ; ^b ; Synn&#xf6 ; ve Carlson^a ; ^c ; ^d ; Robert Boldt^a ; ^c ; Tuomas Neuvonen^a ; ^e ; Henri Hannula^e ; Jaana Hiltunen^c ; Oili Salonen^f ; Yuan-Ye Ma^g ; Antti Pertovaara^a ; ^{Antti.Pertovaara@helsinki.fi}
• 关键词：Prefrontal cortex ; Middle frontal gyrus ; Navigated transcranial magnetic stimulation ; Sensory gating ; Sensory interference ; Tactile working memory ; Tractography ; Top-down control
• 刊名：Behavioural Brain Research
• 出版年：2011
• 出版时间：1 June 2011
• 年：2011
• 卷：219
• 期：2
• 页码：387-390
• 全文大小：222 K

文摘

Tactile working memory (WM) is improved by increasing top-down suppression of interfering sensory processing in S1 via a link from the middle frontal gyrus (MFG) to S1. Here we studied in healthy subjects whether the efficacy of top-down suppression varies with submodality of sensory interference. Navigated stimulation of the MFG-S1 link significantly improved tactile WM performance when accompanied by tactile but not visual interference of memory maintenance.