Primary synovial sarcoma of the scalp: Report of case with a clinicopathological and molecular cytogenetic study

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• 作者：Pingping Hu^a ; ^b ; Miao Chen^a ; ^{18912802271@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jian Wang^c
• 关键词：Synovial sarcoma ; Scalp ; Primary ; Differential diagnosis ; Head neoplasm
• 刊名：Experimental and Molecular Pathology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：101
• 期：1
• 页码：100-104
• 全文大小：1266 K

文摘

Synovial sarcoma (SS) arising primarily in the scalp was scarcely reported. Here we described a subcutaneous mass in the right parietal region of the scalp of a 39 year-old male patient. It has been present for 10 years and enlarged recently. It was initially suspected as hemangioma by magnetic resonance imaging (MRI), but the histological examination revealed a sarcoma rich of spindle cells reminiscent of SS. Therefore, immunohistochemistry, florescence in site hybridization (FISH), reverse transcription-polymerase chain reaction (RT-PCR) and DNA sequencing were performed to determine the final diagnosis as biphasic SS. The detailed description of primary scalp SS might help differential diagnosis of scalp soft tumors.