All Ribosomes Are Created Equal. Really?

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• 作者：Thomas Preiss¹ ; ² ; ^@ ; ^{thomas.preiss@anu.edu.au" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Molecular machine ; ribosome ; protein synthesis ; post-transcriptional regulation ; mass spectrometry
• 刊名：Trends in Biochemical Sciences
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：41
• 期：2
• 页码：121-123
• 全文大小：474 K

文摘

Ribosomes are generally thought of as molecular machines with a constitutive rather than regulatory role during protein synthesis. A study by Slavov et al. [1] now shows that ribosomes of distinct composition and functionality exist within eukaryotic cells, giving credence to the concept of ‘specialized’ ribosomes.