Distigmine bromide induced acute psychotic disorder in a patient with multiple sclerosis
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- 作者：Himmerich ; Hubertus ; Szegedi ; Armin ; Klawe ; Christoph ; Anghelescu ; Ion ; Mü ; ller ; Matthias J.
- 关键词：Distigmine bromide ; Multiple sclerosis ; Blood-brain barrier
- 刊名：European Psychiatry
- 出版年：2003
- 出版时间：October, 2003
- 年：2003
- 卷：18
- 期：6
- 页码：318-319
- 全文大小：95.6 K
文摘
A female patient with multiple sclerosis (MS) suffered from an acute psychotic disorder after taking distigmine bromide for detrusor dysfunction. She showed a dramatic relief of her symptoms after the medication, distigmine bromide, was stopped. Distigmine is not supposed to penetrate the blood-brain barrier (BBB). However, in MS patients a leakage of the BBB could be hypothesized.