A comparison study of macrocyclic hosts functionalized reduced graphene oxide for electrochemical recognition of tadalafil
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- 作者：Hui Zhaoa ; 1 ; Long Yangb ; 1 ; Yucong Lib ; Xin Ranb ; Hanzhang Yeb ; Genfu Zhaob ; Yanqiong Zhangb ; Feng Liua ; Can-Peng Lib ; lcppp1974@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：β-cyclodextrin ; p-Sulfonated calix[6]arene ; Reduced graphene oxide ; Inclusion complex ; Molecular recognition
- 刊名：Biosensors and Bioelectronics
- 出版年：2017
- 出版时间：15 March 2017
- 年：2017
- 卷：89
- 期：part_P1
- 页码：361-369
- 全文大小：2191 K
文摘
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The recognition of tadalafil by β-CD and SCX6 was compared.
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SCX6@RGO exhibited excellent sensing performance and supramolecular recognition capability.
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A sensitive electrochemical sensing platform was developed based on the SCX6@RGO.
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The β-CD/tadalafil and SCX6/tadalafil complexes were studied by molecular docking.
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The binding mode between β-CD/SCX6 and tadalafil was clarified.