TAGLN expression is deregulated in endometriosis and may be involved in cell invasion, migration, and differentiation

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• 作者：Gabriela dos Santos Hidalgo ; M.Sc.^a ; ^{ghidalgo@usp.br} ; Juliana Meola ; Ph.D.^a ; Jú ; lio Cé ; sar Rosa e Silva ; M.D. ; Ph.D.^a ; Clá ; udia Cristina Paro de Paz ; Ph.D.^b ; Rui Alberto Ferriani ; M.D. ; Ph.D.^a
• 关键词：Cell differentiation ; cell invasion ; cell migration ; endometriosis ; gene expression ; TAGLN
• 刊名：Fertility and Sterility
• 出版年：2011
• 出版时间：September, 2011
• 年：2011
• 卷：96
• 期：3
• 页码：700-703
• 全文大小：213 K

文摘

We found an increased expression of the TAGLN gene in endometriotic lesions compared with the eutopic endometrium of the same patients by real-time polymerase chain reaction. It is possible that this deregulation contributes to the development and maintenance of endometriosis by being involved in the pathways of organization of cytoskeletal architecture.