Cytomegalovirus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation is Associated with a Reduced Risk of Relapse in Patients with Acute Myeloid Leukemia Who Survived to Day 100 after Transplantation: The Japan Society for Hematopoietic Cell Transplantation Transplantation-related Complication Working Group
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- 作者：Katsuto Takenaka1 ; takenaka@intmed1.med.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Tetsuya Nishida2 ; Yuki Asano-Mori3 ; Kumi Oshima4 ; Kazuteru Ohashi5 ; Takehiko Mori6 ; Heiwa Kanamori7 ; Koichi Miyamura8 ; Chiaki Kato9 ; Naoki Kobayashi10 ; Naoyuki Uchida3 ; Hirohisa Nakamae11 ; Tatsuo Ichinohe4 ; Yasuo Morishima12 ; Ritsuro Suzuki13 ; Takuhiro Yamaguchi14 ; Takahiro Fukuda15
- 关键词：Cytomegalovirus ; Allogeneic hematopoietic stem cell transplantation ; Risk of relapse ; Nonrelapse mortality
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：21
- 期：11
- 页码：2008-2016
- 全文大小：778 K
文摘
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Cytomegalovirus reactivation was associated with decreased incidence of relapse in patients with acute myeloid leukemia who survived to day 100 after allogeneic hematopoietic stem cell transplantation
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A beneficial effect of cytomegalovirus reactivation on subsequent risk of relapse was observed in patients with acute myeloid leukemia but not in those with other hematological malignancies
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Cytomegalovirus reactivation was associated with increased nonrelapse mortality, translating into lower overall survival