Utility of ionic liquid for Geotrichum candidum

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• 作者：Takamasa Tanaka ; Noritaka Iwai ; Tomoko Matsuda ; Tomoya Kitazume
• 关键词：Ionic liquid ; Enantiomer ; Deracemization ; Enantioselective oxidation
• 刊名：Journal of Molecular Catalysis B: Enzymatic
• 出版年：2009
• 出版时间：May 2009
• 年：2009
• 卷：57
• 期：1-4
• 页码：317-320
• 全文大小：197 K

文摘

Ionic liquids have recognized as a solvent for Geotrichum candidum-catalyzed optical resolution and/or deracemization of racemic secondary alcohols, giving optically active alcohols. The immobilized Geotrichum candidum proceeded the enantioselective oxidation of alcohols, producing chiral alcohols in an ionic liquid. Further, deracemization of racemic alcohols was proceeded to give the corresponding chiral alcohols in high yield with excellent stereoselectivity by the Geotrichum candidum–NaBH₄ system in the mixture of MES buffer solution and ionic liquid.