Serum level of LOX-1 ligand containing ApoB is associated with increased carotid intima-media thickness in Japanese community-dwelling men, especially those with hypercholesterolemiaLOX-1 ligand and IMT in Japanese
详细信息 查看全文
- 作者：Tomonori Okamura ; MDa ; b ; okamura@z6.keio.jp" class="auth_mail" title="E-mail the corresponding author ; Katsuyuki Miura ; MDb ; c ; Tatsuya Sawamura ; MDd ; e ; Aya Kadota ; MDb ; c ; Takashi Hisamatsu ; MDb ; c ; Akira Fujiyoshi ; MDb ; Naomi Miyamatsu ; PhDf ; Naoyuki Takashima ; MDb ; Naoko Miyagawa ; PhDb ; Takashi Kadowaki ; MDb ; Takayoshi Ohkubo ; MDg ; Yoshitaka Murakami ; PhDh ; Yasuyuki Nakamura ; MDi ; Hirotsugu Ueshima ; MDb ; c ; for the SESSA Research Group
- 关键词：LOX-1 ligand containing ApoB ; Lectin-like oxidized LDL receptor 1 ; Hypercholesterolemia ; Population ; Risk factors ; Carotid intima-media thickness
- 刊名：Journal of Clinical Lipidology
- 出版年：2016
- 出版时间：January-February 2016
- 年：2016
- 卷：10
- 期：1
- 页码：172-180.e1
- 全文大小：210 K
文摘
- •
We recruited 992 community-dwelling Japanese men with a mean age of 63.8 ± 10.0 years.
- •
The serum levels of LAB and carotid intima-media thickness were measured.
- •
LAB was associated with carotid IMT after adjustment for traditional risk factors.
- •
The association was diminished by further adjustment for total cholesterol (TC).
LAB was associated with IMT in high TC participants after further adjustment for TC.