Ameloblastic carcinoma, secondary type: a case report

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• 作者：Kazunari Karakida ; Takayuki Aoki ; Haruo Sakamoto ; Miho Takahashi ; Tadashi Akamatsu ; Go Ogura ; Yasutomo Sekido ; Yoshihide Ota
• 刊名：Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：110
• 期：6
• 页码：e33-e37
• 全文大小：2022 K

文摘

Malignant variants of ameloblastoma include metastasizing ameloblastoma, which microscopically appears benign but has metastasized and ameloblastic carcinoma that exhibits malignant histopathologic features. Ameloblastic carcinoma is classified into 2 types: a primary odontogenic malignancy and a secondary type resulting from malignant transformation of ameloblastoma. Most secondary ameloblastic carcinomas result from malignant transformation of a primary lesion after repeated postsurgical recurrences. Therefore it is rare to find an untreated secondary type presenting with histologic features of malignant transformation from an earlier benign lesion. We experienced a rare case of ameloblastic carcinoma, secondary type which might arise in an untreated ameloblastoma. The mechanism by which a preexisting benign ameloblastoma goes through a malignant transformation is also described.