Prediction of Venous Thromboembolism after Total Knee Arthroplasty Using Dielectric Blood Coagulometry

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• 作者：Hidetoshi Uchiyama¹ ; ^{uchiyama.srg1@tmd.ac.jp} ; Yoshinori Inoue¹ ; Isao Uchimura² ; Tomomasa Nakamura³ ; Toshifumi Kudo¹ ; Takeshi Muneta³ ; Tatsuyuki Kawano¹
• 刊名：Annals of Vascular Surgery
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：38
• 期：Complete
• 页码：286-292
• 全文大小：952 K
• 卷排序：38

文摘

Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) frequently occurs in patients undergoing total knee arthroplasty (TKA). This study aimed to evaluate the efficacy of dielectric blood coagulometry (DBCM) as a new technique for predicting postoperative VTE.MethodsThirty patients undergoing TKA were enrolled. DVT was diagnosed by ultrasonography preoperatively and on the fourth or fifth postoperative day. Enhanced computed tomography was performed to detect PE on the fourth postoperative day. The day after surgery, a blood sample was measured by DBCM. All patients received fondaparinux or low-molecular-weight heparin for postoperative thromboprophylaxis.ResultsEighteen of the 30 patients had DVT postoperatively, and 10 had asymptomatic PE. Seven patients had both DVT and PE. The patterns of permittivity as a function of time and frequency from the DBCM measurement were different between patients with and without VTE. The sensitivity and specificity of the parameter constructed from a set of permittivities at the frequencies of 2.5 kHz, 1 MHz, and 10 MHz were 90% and 78%, respectively.ConclusionsDBCM was effective and efficient for predicting VTE after TKA.