High temperature induces apoptosis and oxidative stress in pufferfish (Takifugu obscurus) blood cells
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- 作者：Chang-Hong Chenga ; 1 ; Fang-Fang Yangb ; 1 ; Shao-An Liaoa ; Yu-Tao Miaoa ; Chao-Xia Yea ; chaoxia_ye@yahoo.com.cn" class="auth_mail" title="E-mail the corresponding author ; An-Li Wanga ; wanganl@scnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jia-Wen Tana ; Xiao-Yan Chena
- 关键词：Takifugu obscurus ; High temperature ; Apoptosis ; Oxidative stress
- 刊名：Journal of Thermal Biology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：53
- 期：Complete
- 页码：172-179
- 全文大小：1299 K
文摘
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High temperature induced apoptosis and oxidative stress in pufferfish blood cells.
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Apoptosis had a high correlation with the increased ROS and cf-Ca2+production.
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The p53–Bax pathway and the caspase-dependent apoptotic pathway were involved in high temperature stress-induced apoptosis in pufferfish blood cells.
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Antioxidant enzymes and heat shock proteins protected the blood cells against oxidative stress.