Furan in the baby-food samples purchased from the Finnish markets – Determination with SPME–GC–MS

详细信息    查看全文

• 作者：Marika Jestoi ; Talvikki J&#xe4 ; rvinen ; Eila J&#xe4 ; rvenp&#xe4 ; &#xe4 ; Heli Tapanainen ; Suvi Virtanen ; Kimmo Peltonen
• 关键词：Furan ; Baby-food ; Solid-phase microextraction ; GC– ; MS
• 刊名：Food Chemistry
• 出版年：2009
• 出版时间：1 December 2009
• 年：2009
• 卷：117
• 期：3
• 页码：522-528
• 全文大小：228 K

文摘

A method applying solid-phase microextraction followed by gas chromatography–mass spectrometric determination was in-house validated and used to study furan concentrations in baby-food samples purchased from the Finnish markets. The validation parameters showed that the method was well applicable for the reliable analysis of furan. Furan was analysed in 21 different baby-food samples as three independent replicates. The mean levels of furan varied between 4.7 and 90.3 μg kg⁻¹ being well in accordance with the levels reported in other studies. The mean concentrations of similar product formulas based on their ingredients were 9.2, 37.0 and 49.6 μg kg⁻¹ for fruit-, vegetables- and meat-containing baby-foods, respectively. According to the statistical analyses, fruit-based baby-food samples had significantly lower concentrations of furan as compared to other formulas. Based on our exercise, it seems that a low margin of safety exists between the extreme worst case infant exposures and the deduced NOAEL of furan on experimental animals, particularly for a clear rodent carcinogen.