MiR-27b downregulation in TamR cells is a result of promoter methylation.
Enforced miR-27b expression sensitizes TamR cells to tamoxifen.
Enforced miR-27b expression inhibits cell invasion and reverses EMT.
MiR-27b directly targets HMGB3 in breast cancer cells.
Silencing of HMGB3 phenocopies the effects of miR-27b in TamR cells.