Giant seminoma case with very small yolk sac and embryo carcinoma components, detected by intensive histopathological examination

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• 作者：Takeo Nakaya ; MD^a ; ^b ; ^d ; ^{nakaya@jichi.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Shuichiro Kobayashi ; MD^c ; Satoshi Kitahara ; MD^c ; Akira Tanaka ; MD^d ; Hiroshi Kamma ; MD^a ; Akio Komatsu ; MD^b
• 关键词：Giant seminoma ; Yolk sac tumor ; Embryo carcinoma ; Intensive histological examination
• 刊名：Human Pathology: Case Reports
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：5
• 期：Complete
• 页码：29-33
• 全文大小：1481 K

文摘

We experienced the giant seminoma with 18 × 10 × 10 cm sized and about 2.6 kg weight of 25 year old patient. We intensively examined the histological tissue type distributions in this giant seminoma. Most of the tumor consisted of seminoma components. In addition, the tumor included the very small fragments of yolk sac tumor and embryonal carcinoma component at the root part of the seminoma mass. This shows that intensive histological examination may contribute to the finding of other embryonic component of the large seminoma. This may show that leaving the seminoma growing may generate the other embryonic tumor component, not always big enough to find out in a routine procedure, during the growth, in the different way from the original mixed cell germ tumor.