Enhanced CT imaging of human laryngeal squamous carcinoma and indirect CT lymphography imaging using PEGylated PAMAM G5·NH2-entrapped gold nanoparticles as contrast agent
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- 作者：Fang Shia ; b ; Chen Pengc ; Yue Yanga ; b ; Yan Shaa ; Xiangyang Shid ; e ; f ; Haitao Wua ; b ; haitaowu1103@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dendrimers ; Gold nanoparticles ; In vivo CT imaging ; Tumors ; Indirect CT lymphography
- 刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects
- 出版年：2016
- 出版时间：20 May 2016
- 年：2016
- 卷：497
- 期：Complete
- 页码：194-204
- 全文大小：3845 K
文摘
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Hep-2 xenograft tumor model and the SLN in rabbits after administration of the PEGylated Au DENPs could be efficient imaged.
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The formed PEG-Au DENPs were non-cytotoxic in the given concentration range.
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The PEG-Au DENPs could be uptaken predominantly in the lyososomes of the cells.