The heterozygous R1441C mutation of leucine-rich repeat kinase 2 gene in a Chinese patient with Parkinson disease: A five-year follow-up and literatures review
Identify pathogenic variants of LRRK2 in Chinese EOPD patients and did find one R1441C mutation. First report of R1441C mutation in China. The patient had been followed up for 5 years and performed PET-DAT twice. R1441C carrying patients were distinguishable from IPD patients.