Determination of aminoglycoside residues in milk and muscle based on a simple and fast extraction procedure followed by liquid chromatography coupled to tandem mass spectrometry and time of flight mass spectrometry
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- 作者：Juliana Bazzan Arsanda ; b ; juarsand@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Louí ; se Janka ; b ; Magda Targa Martinsa ; Rodrigo Barcellos Hoffa ; Fabiano Barretoa ; Tâ ; nia Mara Pizzolatob ; Carla Sirtorib
- 关键词：Aminoglycosides ; Residues ; Milk ; Muscle ; LC&ndash ; MS/MS ; Time of flight mass spectrometry
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：154
- 期：Complete
- 页码：38-45
- 全文大小：455 K
文摘
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This paper describes a method for determine ten aminoglycosides in milk and muscle.
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An extraction method was developed, based on liquid–liquid extraction without SPE or evaporation.
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LC–MS/MS was used to carry out quantitative analysis, with LODs between 5 and100 ng g−1.
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LC-QTOF-MS was used to screening purposes, with CCβ values between 25 and 250 ng g−1.
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The proposed method is simple, easy, and adequate for routine analysis.