Shrimp miRNAs regulate innate immune response against white spot syndrome virus infection
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- 作者：Napol Kaewkascholkula ; Kulwadee Somboonviwatb ; Shuichi Asakawac ; Ikuo Hironod ; Anchalee Tassanakajona ; e ; Kunlaya Somboonwiwata ; e ; kunlaya.s@chula.ac.th" class="auth_mail" title="E-mail the corresponding author
- 关键词：Penaeus monodon ; Black tiger shrimp ; microRNA ; White spot syndrome virus ; Shrimp immunity ; RNA interference
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：60
- 期：Complete
- 页码：191-201
- 全文大小：1713 K
文摘
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miRNAs from WSSV-infected Penaeus monodon hemocyte and their target immune-related mRNAs were identified.
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The expression of pmo-miR-315 and pmo-miR-750, were highly responsive to WSSV infection in hemocyte.
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The miRNA/mRNA interaction of the highly conserved miRNA, pmo-bantam and KuSPI was confirmed.
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pmo-bantam was a negative regulator of KuSPI in lymphoid organ of WSSV-infected shrimp.