A benzimidazole derivative (RCB20) in vitro induces an activation of energetic pathways on Taenia crassiceps (ORF strain) cysticerci

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• 作者：Carolina Miguel Fraga^a ; ^{carolinamfraga@gmail.com} ; Tatiane Luiza da Costa^a ; ^{tatiane_luiza@yahoo.com.br} ; Ana Maria de Castro^a ; ^{amaria.ana@gmail.com} ; Olivia Reynoso-Ducoing^b ; ^{oard_2000@hotmail.com} ; Javier Ambrosio^b ; ^jrah@unam.mx ; Alicia Herná ; ndez-Campos^c ; ^{hercam@unam.mx} ; Rafael Castillo^c ; ^{rafaelc@unam.mx} ; Marina Clare Vinaud^a ; ^{marinavinaud@gmail.com}
• 关键词：Taenia crassiceps ; Energetic metabolism ; RCB20 ; Albendazole sulfoxide
• 刊名：Experimental Parasitology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：172
• 期：Complete
• 页码：12-17
• 全文大小：953 K
• 卷排序：172

文摘

Cysticerci exposed to RCB20 presented a greater induction of glycolylis. Cysticerci exposed to RCB20 presented a greater induction of the TCA cycle. RCB20 induced the energetic pathways. RCB20 presents a greater effect on the metabolism than ABZSO. RCB20 is a promising substitute for ABZSO.