Evidence of cerebrospinal fluid abnormalities in patients with depressive syndromes
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- 作者：Dominique Endres<sup>asup><sup> ; sup><sup>dominique.endres@uniklinik-freiburg.de" class="auth_mail" title="E-mail the corresponding authorsup> ; Evgeniy Perlov<sup>asup> ; Rick Dersch<sup>bsup> ; Annette Baumgartner<sup>bsup> ; Tilman Hottenrott<sup>bsup> ; Benjamin Berger<sup>bsup> ; Oliver Stich<sup>bsup><sup> ; sup><sup>1sup> ; Ludger Tebartz van Elst<sup>asup><sup> ; sup><sup>1sup>
- 关键词：Cerebrospinal fluid ; Depressive syndrome ; Blood-brain-barrier-dysfunction ; Immunological encephalopathy
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：198
- 期：Complete
- 页码：178-184
- 全文大小：290 K
文摘
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We detected cerebrospinal fluid (CSF) alterations in 56% of depressive syndromes.
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Four percent displayed increased CSF white blood cell (WBC) counts. Oligoclonal bands in the CSF were detected in 6.5%.
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Forty six percent had increased protein concentrations, and 19.4% had pathological albumin quotients.
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Suicidal tendencies correlated with an increased WBC count.
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More research is necessary in better controlled conditions.