Cytotoxic effects of tebufenozide in vitro bioassays
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- 作者：Xiaoqin Yua ; 1 ; Yang Zhanga ; 1 ; Mingjun Yanga ; Junfu Guoa ; Wenping Xua ; Jufang Gaob ; Yaxiao Lic ; Liming Taoa ; taolm@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pesticide ; Environmental toxicity ; Cytotoxic effects ; Tebufenozide ; Apoptosis
- 刊名：Ecotoxicology and Environmental Safety
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：129
- 期：Complete
- 页码：180-188
- 全文大小：1824 K
文摘
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The present study reveals the non-selective cytotoxic effects of tebufenozide.
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We demonstrate for the first time that tebufenozide has ability to induce apoptosis.
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A mitochondrial-dependent intrinsic pathway contributes to tebufenozide induced apoptosis.