Differences in biochemical bone markers by diabetes type and the impact of glucose
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- 作者：Jakob Starup-Lindea ; b ; ; Simon Lykkeboec ; Sø ; ren Gregersena ; Ellen-Margrethe Hauged ; Bente Lomholt Langdahla ; Aase Handbergb ; c ; Peter Vestergaardb ; e
- 关键词：BMD ; bone mineral density ; CTX ; C-terminal cross-linked telopeptide of type-I collagen ; FGF-23 ; fibroblast growth factor-23 ; OC ; osteocalcin ; OPG ; osteoprotegerin ; P1NP ; procollagen type 1 amino terminal propeptide ; RANKL ; Receptor Activator of Nuclear factor Kappa beta Ligand ; T1D ; type 1 diabetes ; T2D ; type 2 diabetes ; ucOC ; undercarboxylated osteocalcin
- 刊名：Bone
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：149-155
- 全文大小：741 K
文摘
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Bone turnover markers were lower in patients with type 2 diabetes compared to patients with type 1 diabetes.
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Bone turnover markers were negatively associated with p-glucose.
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P-osteoprotegerin was positively associated with p-glucose.
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Bone turnover in diabetes patients may be in a state of dependency on glucose levels.
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Prospective studies evaluating bone turnover markers and p-glucose in diabetes patients are needed.