Preparation of superficially porous core-shell silica particle with controllable mesopore by a dual-templating approach for fast HPLC of small molecules
CSSMs were synthesized with a dual-templating approach for the first time. The pore size of the CSSMs can be enlarged to 10.6 nm with the addition of TOMAB. The mesopore channels of the CSSMs are perpendicular to the particles surface. The synthesized CSSMs can be used in fast separation of small molecules.