Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis
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- 作者：Sachiko Bandoa ; Daiju Fukudaa ; daiju.fukuda@tokushima-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Takeshi Soekia ; Sachiko Nishimotob ; Etsuko Uematsua ; Tomomi Matsuuraa ; Takayuki Isea ; Takeshi Tobiumea ; Koji Yamaguchia ; Shusuke Yagia ; Takashi Iwasea ; Hirotsugu Yamadaa ; Tetsuzo Wakatsukia ; Michio Shimabukuroc ; Masataka Sataa
- 关键词：Atherosclerosis ; Adipose tissue ; Inflammation ; NLRP3 inflammasome ; Lifestyle-related disease
- 刊名：Atherosclerosis
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：242
- 期：2
- 页码：407-414
- 全文大小：1083 K
文摘
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NLRP3 expression in SAT was higher in patients with lifestyle-related diseases.
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NLRP3 expression in SAT correlated negatively with serum adiponectin level.
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CAD patients showed higher NLRP3 expression in SAT than non-CAD patients.
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NLRP3 expression in SAT and HbA1c were predictors of coronary atherosclerosis.