Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer
详细信息 查看全文
- 作者：J. Haumanna ; b ; J.W. Geurtsa ; S.M.J. van Kuijkc ; B. Kremerd ; E.A. Joostena ; e ; M.H.J. van den Beuken-van Everdingena ; f ; m.vanden.beuken@mumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Methadone ; Fentanyl ; Head-and-neck cancer ; Cancer pain ; NMDA receptor antagonist
- 刊名：European Journal of Cancer
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：121-129
- 全文大小：694 K
文摘
- •
Methadone results in a better and faster pain relief in the treatment of oncological pain with a neuropathic component as compared with fentanyl.
- •
The mean decrease in pain interference is more prominent in methadone treated patients than in fentanyl treated patients.
- •
At 1 week significant more patients in the methadone group had a 50% pain relief.
- •
There was no significant difference between the groups in percentage of patients with severe side effects.