Differential effect of chronic stress on mouse hippocampal memory and affective behavior: Role of major ovarian hormones

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• 作者：Bhanu Chandra Karisetty^a ; ¹ ; Swati Maitra^a ; ¹ ; Abhipradnya Bipin Wahul^a ; Anusha Musalamadugu^a ; Nitin Khandelwal^b ; Sumasri Guntupalli^a ; Ramya Garikapati^a ; Thatiparthi Jhansyrani^a ; Arvind Kumar^b ; Sumana Chakravarty^a ; ^{sumana98@gmail.com} ; ^{sumanachak@iict.res.in}
• 关键词：Depression ; Mood disorder ; Cognitive disorder ; Ovariectomy ; 17β-Estradiol ; NMDAR
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：318
• 期：Complete
• 页码：36-44
• 全文大小：1643 K
• 卷排序：318

文摘

Intact and OVX females showed difference in mood disorder sub-phenotypes to CUS. Estrogen alters hippocampal mood and cognition circuitries in female mice. Estrogenic effects appear to be mediated via N-methyl-d-aspartate receptor subunits.