Thermogelling chitosan-collagen-bioactive glass nanoparticle hybrids as potential injectable systems for tissue engineering
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- 作者：Cheisy D.F. Moreira ; Sandhra M. Carvalho ; Herman S. Mansur ; hmansur@demet.ufmg.br" class="auth_mail" title="E-mail the corresponding author ; Marivalda M. Pereira mpereira@demet.ufmg.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biocomposite ; Thermosensitive hydrogels ; Biomaterial ; Scaffolds ; Composite ; Collagen
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：58
- 期：Complete
- 页码：1207-1216
- 全文大小：1778 K
文摘
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Chitosan-based hydrogels were prepared using collagen and bioactive glass (BG).
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Novel composites made of chitosan, collagen and BG nanoparticles were produced.
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Nanocomposites were non cytotoxic tested with 2 cell lines using in vitro assays.
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The hydrogel composites presented thermogelling behavior at 37 °C.
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Cytocompatible composite hydrogels were produced with promising perspectives as injectable systems.