MAP Kinase Module: The Ksr Connection

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• 作者：Franç ; ois Roy ; Marc Therrien
• 关键词：CELLBIO ; DNA ; RNA
• 刊名：Current Biology
• 出版年：2002
• 出版时间：30 April 2002
• 年：2002
• 卷：12
• 期：9
• 页码：R325-R327
• 全文大小：148 K

文摘

Ksr has been genetically defined as a component of the Ras/MAP kinase pathway, but its role has been unclear. New studies now provide evidence that Ksr is important for signal transmission within the MAP kinase module, where it apparently acts as a location-regulated scaffold connecting MEK to Raf.