Geographic variation in the elicitin-like glycoprotein, ELI025, of Pythium insidiosum isolated from human and animal subjects
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- 作者：Tassanee Lerksuthirata ; c ; Tassanee Lohnoob ; Thidarat Rujirawata ; b ; c ; Wanta Yingyongb ; Nujarin Jongrujab ; Theerapong Krajaejuna ; mr_en@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pythium insidiosum ; Pythiosis ; ELI025 ; Elicitin ; Geographic variation
- 刊名：Infection, Genetics and Evolution
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：35
- 期：Complete
- 页码：127-133
- 全文大小：1242 K
文摘
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Among pathogenic oomycetes, Pythium insidiosum is known to infect humans.
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Elicitins form a unique group of proteins found only in oomycetes.
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The secreted form of elicitin protein, ELI025, was detected in all P. insidiosum strains tested.
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Some P. insidiosum strains lack the glycosylated form of secreted ELI025.
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Some patients fail to mount a detectable antibody response to ELI025.