- 作者：Nadine Linthout ; Samuel Bral ; Iwein Van de Vondel ; Dirk Verellen ; Koen Tournel ; Thierry Gevaert ; Michael Duchateau ; Truus Reynders ; Guy Storme
- 关键词：Breathing synchronized irradiation ; IGRT ; Lung cancer ; Hypo-fractionated SBRT
- 刊名：Radiotherapy and Oncology
- 出版年：2009
- 出版时间：June 2009
- 年：2009
- 卷：91
- 期：3
- 页码：330-335
- 全文大小：407 K
PurposeThe feasibility to use visually guided voluntary breath-hold with and without audio assistance to reduce the total treatment time was evaluated.Materials and methods
Patients referred for gated SBRT received hypofractionation schedules for lung or liver treatments. The patients were treated with the Novalis® system (BrainLAB AG, Feldkirchen, Germany) and IGRT was performed with ExacTrac5.0/NovalisBody® allowing gated irradiation. Video glasses, used for visual feedback to guide voluntary breath-hold, allowed additional audio assistance during treatment.
The technique was applied for 25 patients of whom 9 were treated in free breathing, 7 had only visual feedback and another 9 had both audio and visual feedback.
Results
The delivery time of gated treatment during free breathing had an average value of 1.7 min/100 MU (SD 0.6 min/100 MU). The introduction of visual feedback reduced the average delivery time to 1.4 min/100 MU (SD 0.4 min/100 MU). The treatments with additional audio assistance indicated a significant reduction (p = 0.004) of the average delivery time to 0.9 min/100 MU (SD 0.2 min/100 MU).
Conclusion
The introduction of visually guided voluntary breath-hold with audio assistance led to treatment times for gated radiation therapy approaching conformal beam delivery times, which made gated treatments applicable in conventional treatment time slots.