Preparation and characterisation of a quinone-functionalised polythiophene film on a modified electrode. Application to the potentiometric determination of glutathione and cysteine concentrations
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- 作者：Sté ; phanie É ; tienne ; Muriel Matt ; Thierry Oster ; Mohammad Samadi ; Marc Beley
- 关键词：Quinone-functionalised polythiophene ; Modified electrode ; Glutathione/cysteine electrochemical sensor
- 刊名：Tetrahedron
- 出版年：2008
- 出版时间：29 September 2008
- 年：2008
- 卷：64
- 期：40
- 页码：9619-9624
- 全文大小：376 K
文摘
The new compound 3-((2,5-dimethoxyphenyl)ethynyl)thiophene has been synthesised by Sonogashira coupling. A modified electrode coated with a polythiophene film bearing a quinone moiety was obtained by electropolymerisation of the thienyl group followed by anodic oxidation of para-dimethoxyphenyl group. The cyclovoltammetric response resulting from the reaction of glutathione with the benzoquinone moiety was investigated. The responses of the modified electrode as a new potentiometric sensor of reduced thiols are proposed.