Migration and interaction tracking for quantitative analysis of phagocyte-pathogen confrontation assays

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• 作者：Susanne Brandes^a ; ^b ; Stefanie Dietrich^a ; ^b ; Kerstin Hü ; nniger^c ; Oliver Kurzai^c ; ^d ; Marc Thilo Figge ; ^a ; ^b ; ^{thilo.figge@leibniz-hki.de}
• 关键词：Cell tracking ; Confrontation assay ; Phagocytosis ; Polymorphonuclear neutrophils (PMNs) ; Candida glabrata
• 刊名：Medical Image Analysis
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：36
• 期：Complete
• 页码：172-183
• 全文大小：1946 K
• 卷排序：36

文摘

A framework for analyzing confrontation assays is proposed. Multi-channel time-lapse microscopy videos are segmented and cells are tracked. Tracking of fungal cells and PMNs reveals insights into interactive cell behavior.