We reduced a kinetic model of 22 parameters and 21 species to a single equation.
We analyzed the fraction of peroxiredoxin oxidized by H2O2.
We estimated length and time scales of H2O2 that is generated within the cytosol.
We used a H2O2 consumption parameter and diffusivity to obtain scale estimates.
Cytosolic H2O2 is consumed within ~1 ms and ~1 μM of its generation.