Expression of Cryptosporidium parvum thioredoxin peroxidase in COS-7 cells confers radioprotection
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- 作者：Semie Honga ; 1 ; Jae-Hwan Kimb ; 1 ; Sejoung Yoonb ; Kyoungjin Kimb ; Seobo Simb ; Woo-Yoon Parkc ; Jae-Ran Yub ; maria205@kku.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cryptosporidium parvum ; Thioredoxin peroxidase ; Radioprotection
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：163
- 期：Complete
- 页码：8-15
- 全文大小：1538 K
文摘
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CpTPx was transfected to COS-7 cells.
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CpTPx mediated higher cell survival rates among the experimental groups.
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Potent antioxidant and DNA damage protection activity of CpTPx are conserved in cells.
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Apoptotic change was reduced in CpTPx transfected COS-7 after irradiation.
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Transfected CpTPx contribute to radioprotection in COS-7 cells.