Pyrogallol abates VSMC migration via modulation of Caveolin-1, matrix metalloproteinase and intima hyperplasia in carotid ligation mouse

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• 作者：Yu-Dong Map>ap> ; Varadharajan Thiyagarajanp>ap> ; May-Jywan Tsaip>bp> ; Sheng-I Luep>ap> ; Yi-Chen Chiap>cp> ; Song-Kun Shyuep>dp> ; Ching-Feng Wengp>ap>p> ; p>p>cfweng@mail.ndhu.edu.twp>
• 关键词：Pyrogallol ; Doxycycline ; Anti-atherogenic ; Caveolin-1 ; Vascular smooth muscle cells ; Matrix metalloproteinase
• 刊名：Environmental Toxicology and Pharmacology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：48
• 期：Complete
• 页码：63-75
• 全文大小：4906 K
• 卷排序：48

文摘

Pyrogallol diminishes the severity of neointima hyperplasia. Pyrogallol increases tissue inhibitors of metalloproteinase 1. Pyrogallol up-regulates the expression of MMP-14.