Immune cell subsets at birth may help to predict risk of late-onset sepsis and necrotizing enterocolitis in preterm infants
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- 作者：Konrad Bochenneka ; 1 ; konrad.bochennek@kgu.de" class="auth_mail" title="E-mail the corresponding author ; Esther Frynsa ; 1 ; Boris Wittekindta ; Horst Buxmanna ; Andrea Quaisera ; Doris Fischera ; Thomas Klingebiela ; Ulrike Koehlb ; Rolf Schloessera ; 2 ; Sabine Hueneckea ; 2
- 关键词：Neonatology ; Cellular immune status ; Necrotizing enterocolitis (NEC) ; Late-onset sepsis ; NK-cells ; Double-negative T cells
- 刊名：Early Human Development
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：93
- 期：Complete
- 页码：9-16
- 全文大小：901 K
文摘
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Prospective study on 40 preterm patients (26-30 weeks)
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Analysis of immune cell subsets within 7 days after birth
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Ten color flow cytometric analysis
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Prediction of LOS and NEC CD56bright and CD56negative CD16positive NK cells, NK cells proportion and CD3 + CD8 + CD45RA + CD62L + T cells
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Early warning system for the bed side clinician