Dermal uptake and percutaneous penetration of ten flame retardants in a human skin ex vivo model
详细信息 查看全文
- 作者：Marie Frederiksena ; mfr@sbi.aau.dk" class="auth_mail" title="E-mail the corresponding author ; Katrin Vorkampb ; Niels Martin Jensenc ; Jens Ahm Sø ; rensenc ; Lisbeth E. Knudsend ; Lars S. Sø ; rensena ; Thomas F. Webstere ; Jesper B. Nielsenf
- 关键词：NBFR ; Brominated flame retardants ; HBCDD ; Skin deposition ; Dermal exposure ; Dechlorane plus
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：162
- 期：Complete
- 页码：308-314
- 全文大小：480 K
文摘
- •
Dermal uptake of novel flame retardants were studied in ex vivo skin model.
- •
Little or no NFRs were detected in the receptor fluid.
- •
Significant deposition in the skin was observed.
- •
Time-lagged penetration from skin depot may occur.
- •
Uptake decreased with increasing log Kow for these very lipophilic compounds.