Interaction network of antimicrobial peptides of Arabidopsis thaliana, based on high-throughput yeast two-hybrid screening
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- 作者：Coralie Damon ; Julia Dmitrieva ; Yordan Muhovski ; Fr¨¦d¨¦ric Francis ; Laurence Lins ; Quentin Ledoux ; William Luwaert ; Istv¨¢n E. Mark¨® ; Sergio Mauro ; Marc Ongena ; Philippe Thonart ; Pascal Veys ; Daniel Portetelle ; Jean-Claude Twizere ; Micheline V ; enbol
- 关键词：Antimicrobial peptide ; Immune system ; Interaction network ; Arabidopsis thaliana ; Yeast two-hybrid ; Plant defence ; Cysteine-rich peptide
- 刊名：Plant Physiology and Biochemistry
- 出版年：2012
- 出版时间：September, 2012
- 年：2012
- 卷：58
- 期：Complete
- 页码：245-252
- 全文大小：675 K
文摘
One mechanism used by plants to respond to infection is the production of antimicrobial peptides (AMPs). In addition to a role in defence, AMPs seem to have other biological functions. Furthermore, the number of cysteine-rich AMP-like peptides appears to have been underpredicted in plant genomes. Such peptides could be involved in plant defence and/or in other biological processes. Here we generated an interaction network between 15 AMPs/AMP-like peptides and ca. 8000 other Arabidopsis thaliana proteins (AtORFeome2.0) and found 53 putative novel interactions. These interactions involve five transcription factors, a subunit of the COP9 signalosome, a heat shock protein, a MAP kinase kinase, a thioredoxin and 4 uncharacterized proteins.