The genetic architecture of a complex trait: Resistance to multiple toxins produced by Bacillus thuringiensis israelensis in the dengue and yellow fever vector, the mosquito Aedes aegypti
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- 作者：Auré ; lie Bonina ; aurelie.bonin@ujf-grenoble.fr" class="auth_mail" title="E-mail the corresponding author ; Margot Parisa ; 1 ; Hé ; lè ; ne Fré ; rotb ; Erica Biancoa ; 2 ; Guillaume Tetreaua ; 3 ; Laurence Despré ; sa
- 关键词：Insecticide resistance ; Genetic architecture ; Complex trait ; Candidate gene ; QTL ; Admixture mapping
- 刊名：Infection, Genetics and Evolution
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：35
- 期：Complete
- 页码：204-213
- 全文大小：1516 K
文摘
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16 QTL regions and six SNP loci were found to be associated with Bti resistance.
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Four QTLs were identified by different methods and are thus particularly robust.
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Five of the detected supercontigs are good candidates for further functional studies.
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The first genetic map based on markers located in genes expressed in larvae was built.
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It showed several assembly discrepancies with the published genome.