Polymorphisms in MIR499A and MIR125A gene are associated with autoimmune thyroid diseases

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• 作者：TianTian Cai^a ; ^b ; Jie Li^c ; Xiaofei An^b ; Ni Yan^b ; Danfeng Li^b ; Yanfei Jiang^b ; Wen Wang^b ; Liangfeng Shi^b ; Qiu Qin^b ; Ronghua Song^b ; Guofei Wang^d ; Wenjuan Jiang^b ; ^{hidyfan81@yahoo.com.cn} ; Jin-an Zhang^b ; ^{zhangjinan@hotmail.com}
• 关键词：Autoimmune thyroid diseases (AITD) ; Graves' disease (GD) ; Hashimoto's thyroiditis (HT) ; Single nucleotide polymorphism (SNP) ; MicroRNAs
• 刊名：Molecular and Cellular Endocrinology
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：440
• 期：Complete
• 页码：106-115
• 全文大小：285 K
• 卷排序：440

文摘

Alleles or genotypes of rs3746444 (miR-499a) and rs12976445 (miR-125a) genes were associated with AITD. No association was found for the tested SNPs of miR-146a for AITD. Potential gene-sex interactions between them and AITD were also observed.