miR-200a-3p regulates TLR1 expression in bacterial challenged miiuy croaker
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- 作者：Yanjin Wang ; Guoliang Xu ; Jingjing Han ; Tianjun Xu ; tianjunxu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：miR-200a-3p ; Toll-like receptor ; TLR1 ; Miiuy croaker ; Regulation ; Signaling pathway
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：63
- 期：Complete
- 页码：181-186
- 全文大小：1241 K
文摘
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Miiuy croaker TLR1 (mmiTLR1) is a putative target of miR-200a-3p.
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The expression profiles of miR-200a-3p and TLR1 showed the opposite trend.
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miR-200a-3p suppressed the luciferase activity of mmiTLR1 3′UTR dual-luciferase reporter.
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NF-κB might provide a link between miR-200a-3p and TLR1 regulation.