Comparative analysis of the small RNA transcriptomes of miiuy croaker revealed microRNA-mediated regulation of TLR signaling pathway response to Vibrio anguillarum infection
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- 作者：Guoliang Xu ; Jingjing Han ; Tianjun Xu ; tianjunxu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Miiuy croaker ; MicroRNA ; Antisense miRNA transcript ; Immune regulation
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：52
- 期：Complete
- 页码：248-257
- 全文大小：1984 K
文摘
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Two sRNA libraries were constructed with or without Vibrio anguillarum infection.
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A total of 378 miRNA precursors were identified in miiuy croaker.
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Antisense miRNA transcripts were found to contribute to the origin of novel miRNAs.
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Differentially expressed miRNAs were identified and validated by qRT-PCR.
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A negative regulation map of TLR signaling mediated by miRNA was constructed.