Metabolic flux analysis of the halophilic archaeon Haladaptatus paucihalophilus
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- 作者：Guangxiu Liua ; b ; Manxiao Zhanga ; b ; Tianlu Moc ; Lian Hed ; Wei Zhanga ; b ; Yi Yud ; yu_yi@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qi Zhangc ; qizhang@sioc.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Wei Dinga ; b ; c ; dingw@lzu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：13C-assisted metabolism analysis ; Glycine biosynthesis ; Halophilic archaea ; Isoleucine biosynthesis ; Lysine biosynthesis
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2015
- 出版时间：27 November 2015
- 年：2015
- 卷：467
- 期：4
- 页码：1058-1062
- 全文大小：493 K
文摘
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Serine hydroxymethyltransferase, threonine aldolase, and glycine cleavage system all contribute to the glycine pool of H. paucihalophilus.
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Threonine and the citramalate pathways contribute equally to the isoleucine biosynthesis in H. paucihalophilus.
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Lysine in H. paucihalophilus is synthesized through the diaminopimelate pathway and not through the α-aminoadipate pathway.
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Glycine biosynthesis is likely unrelated to the cell osmoadaption mechanism.