Angiopoietin-1 attenuates angiotensin II-induced ER stress in glomerular endothelial cells via a Tie2 receptor/ERK1/2-p38 MAPK-dependent mechanism
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- 作者：Xiao Bia ; Jianying Niua ; Wei Dinga ; Minmin Zhangb ; Min Yanga ; minym@163.com" class="auth_mail" title="E-mail the corresponding author ; Yong Gub ; yonggu@vip.163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ER stress ; Cellular dysfunction ; Apoptosis ; Angiopoietins ; Tie2 ; MAPK pathway
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：428
- 期：Complete
- 页码：118-132
- 全文大小：6283 K
文摘
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Angpt1 attenuates ER stress-induced cellular dysfunction and apoptosis in GEnCs.
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Angpt1 decreased the Ang II-induced expression of the ER stress response proteins.
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Angpt1 attenuates ER stress via Tie2 receptor/ERK1/2-p38 MAPK pathways.