The many faces of the mitochondrial TIM23 complex

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• 作者：Dejana Mokranjac ; Walter Neupert
• 关键词：TIM23 complex ; Protein translocase ; Mitochondria ; Protein sorting ; Targeting signals
• 刊名：Biochimica et Biophysica Acta (BBA)/Bioenergetics
• 出版年：2010
• 出版时间：June-July 2010
• 年：2010
• 卷：1797
• 期：6-7
• 页码：1045-1054
• 全文大小：774 K

文摘

The TIM23 complex in the inner membrane of mitochondria mediates import of essentially all matrix proteins and a large number of inner membrane proteins. Here we present an overview on the latest insights into the structure and function of this remarkable molecular machine.