Data on carotid intima-media thickness and lipoprotein subclasses in type 1 diabetes from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC)

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• 作者：Arpita Basu^a ; ¹ ; Alicia J. Jenkins^b ; ^c ; ¹ ; Ying Zhang^d ; Julie A. Stoner^d ; Richard L. Klein^e ; ^f ; Maria F. Lopes-Virella^e ; ^f ; W. Timothy Garvey^g ; Timothy J. Lyons^b ; ^h ; ^{t.lyons@qub.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; The DCCT/EDIC Research Groupⁱ
• 关键词：Lipids and lipoproteins ; Carotid intima-media thickness ; Type 1 diabetes
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：6
• 期：Complete
• 页码：33-38
• 全文大小：198 K

文摘

Type 1 diabetes (T1DM) is associated with increased risk of macrovascular complications. We examined longitudinal associations of serum conventional lipids and nuclear magnetic resonance (NMR)-determined lipoprotein subclasses with carotid intima-media thickness (IMT) in adults with T1DM (n=455) enrolled in the Diabetes Control and Complications Trial (DCCT). Data on serum lipids and lipoproteins were collected at DCCT baseline (1983–89) and were correlated with common and internal carotid IMT determined by ultrasonography during the observational follow-up of the DCCT, the Epidemiology of Diabetes Interventions and Complications (EDIC) study, at EDIC ‘Year 1’ (199–1996) and EDIC ‘Year 6’ (1998–2000). This article contains data on the associations of DCCT baseline lipoprotein profiles (NMR-based VLDL & chylomicrons, IDL/LDL and HDL subclasses and ‘conventional’ total, LDL-, HDL-, non-HDL-cholesterol and triglycerides) with carotid IMT at EDIC Years 1 and 6, stratified by gender. The data are supplemental to our original research article describing detailed associations of DCCT baseline lipids and lipoprotein profiles with EDIC Year 12 carotid IMT (Basu et al. in press) [1].