Peripheral Adaptation Mechanisms in Physical Training and Cardiac Rehabilitation: The Case of a Patient Supported by a Cardiowest Total Artificial Heart

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• 作者：Fabio Bellotto MD¹ ; ² ; Leonida Compostella MD² ; ^{L.compostella@alice.it"" rel=""nofollow} ; Piergiuseppe Agostoni MD ; PhD³ ; Gianluca Torregrossa MD¹ ; Tiziana Setzu MD² ; Antonio Gambino MD¹ ; Nicola Russo MD¹ ; ² ; Giuseppe Feltrin MD¹ ; Vincenzo Tarzia MD¹ ; Gino Gerosa MD¹
• 关键词：Congestive heart failure ; cardiopulmonary exercise testing
• 刊名：Journal of Cardiac Failure
• 出版年：2011
• 出版时间：August 2011
• 年：2011
• 卷：17
• 期：8
• 页码：670-675
• 全文大小：95 K

文摘

Background

The benefits of exercise training in patients with chronic heart failure (CHF) are due to a combination of cardiac and peripheral adaptations. Separating these 2 components is normally impossible, except for patients implanted with total artificial heart (TAH), where cardiac adaptation cannot occur.

Methods and Results

We report the case of a patient implanted with a CardioWest-TAH who underwent a comprehensive strength and endurance training program and was evaluated by repeated peak cardiopulmonary exercise tests. The patient experienced a 24 % increase of peak oxygen consumption and an improvement in recovery kinetics during the training period of 29 months.

Conclusion

This unique situation of a patient with a TAH, and therefore a fixed peak cardiac output, allows us to isolate training-induced changes in the periphery, that suggest greater oxygen extraction and more efficient metabolic gas kinetics during the exercise and recovery phases.