Induction of systemic IFITM3 expression does not effectively control foot-and-mouth disease viral infection in transgenic pigs
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- 作者：Huawei Zhanga ; b ; Haixue Zhengc ; Ping Qiana ; b ; Jinfang Xua ; b ; Xi Yanga ; b ; Rui Zhoua ; b ; Huanchun Chena ; b ; Xiangmin Lia ; b ; lixiangmin@mail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Foot-and-mouth disease virus ; Swine IFITM3 ; Transgenic pigs
- 刊名：Veterinary Microbiology
- 出版年：2016
- 出版时间：15 August 2016
- 年：2016
- 卷：191
- 期：Complete
- 页码：20-26
- 全文大小：1462 K
文摘
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The sIFITM3 transgenic pigs were successfully generated by the handmade cloning.
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The sIFITM3 transgenic pigs as an animal model were evaluated the protection effect against FMDV.
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Induction of systemic sIFITM3 expression does not protect against FMDV infection in pigs.